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Table 2 Comparison of the relative area of collagen deposition in the kidney tissues of animals from each group

From: Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction

Group

Number

Relative area of collagen deposition (%)

Sham-7d

4

4.10 ± 0.3

Sham-14d

4

4.09 ± 0.3

UUO-7d+NC-miR

5

38.17 ± 5.67*

UUO-14d+NC-miR

5

82.52 ± 7.10*

UUO-7d+miR-133b

5

17.83 ± 4.16*,#

UUO-14d+miR-133b

5

40.34 ± 6.18*,#

  1. After Masson’s trichrome staining, 10 fields sampled for each animal were observed under a light microscope (× 400), and the area of each field and the area of collagen fibers stained in green were measured by the Image-Pro Plus software. The relative area of collagen deposition was calculated as follows: area of collagen fibers stained in green/area of field of vision × 100%. *P < 0.01 versus the sham group; #P < 0.01 versus the UUO+NC-miR group