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Table 3 Comparison of renal functions among different groups of animals

From: Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction

Groups

0 days

7 days

14 days

n

BUN (mmol/L)

sCr (μmol/L)

n

BUN (mmol/L)

sCr (μmol/L)

n

BUN (mmol/L)

sCr (μmol/L)

Sham

8

6.9 ± 1.0

17.4 ± 0.7

4

6.7 ± 1.0

17.2 ± 0.7

4

7.0 ± 1.4

17.3 ± 1.0

UUO+NC-miR

10

6.9 ± 1.0

17.7 ± 2.1

5

13.8 ± 1.7*

22.5 ± 1.2*

5

18.3 ± 1.5*

28.4 ± 0.7*

UUO+miR-133b

10

6.7 ± 0.6

17.1 ± 1.9

5

10.3 ± 1.1*,#

20.5 ± 1.7*

5

14.1 ± 1.3*,#

23.2 ± 1.5*,#

  1. BUN blood urea nitrogen, sCr serum creatinine; *P < 0.05 versus the sham group; #P < 0.05 versus the UUO+NC-miR group