Skip to main content

Table 1 Demographic characteristics of the participants

From: Exosomal hsa_circ_0006859 is a potential biomarker for postmenopausal osteoporosis and enhances adipogenic versus osteogenic differentiation in human bone marrow mesenchymal stem cells by sponging miR-431-5p

 

Control

Osteopenia

Osteoporosis

P value

Age (years)

58.32 ± 3.14

59.28 ± 4.06

60.67 ± 6.24

0.058

Body mass index (kg/m2)

23.8 ± 1.2

24.0 ± 2.1

24.1 ± 1.6

0.124

BMD (g/cm2)

0.93 ± 0.08

0.82 ± 0.11

0.65 ± 0.06

0.012

Lumbar spine (L1-L4) T-score

− 0.25 ± 0.04

− 1.82 ± 0.09

− 2.86 ± 0.17

< 0.0001

Lumbar spine (L1-L4) Z-score

− 0.26 ± 0.12

− 1.54 ± 0.03

− 2.76 ± 0.10

< 0.0001

PTH (pg/ml)

38.6 ± 12.4

36.9 ± 11.3

36.8 ± 12.2

> 0.05

25(OH) D (ng/ml)

23.6 ± 4.9

24.2 ± 3.8

23.9 ± 5.8

> 0.05

β-CTx (pg/ml)

558.6 ± 43.1

698.7 ± 52.1

808.4 ± 37.6

< 0.0001

tP1NP (ng/ml)

29.33 ± 3.21

45.22 ± 2.14

59.12 ± 4.02

0.018

Osteocalcin (ng/ml)

7.99 ± 1.08

13.55 ± 2.61

19.02 ± 3.10

0.002

Calcium (mmol/L)

2.43 ± 0.12

2.38 ± 0.07

2.39 ± 0.09

> 0.05

Inorganic phosphorus (mmol/L)

1.21 ± 0.08

1.20 ± 0.06

1.22 ± 0.04

> 0.05