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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: METTL3-mediated m6A modification regulates cell cycle progression of dental pulp stem cells

Fig. 4

Bioinformatic analysis of METTL3 knockdown in DPSCs. a Volcano plots of differentially expressed genes (DGEs) in shCTR and shMETTL3-DPSCs (vertical lines represent > 2.0 fold change, horizontal lines for p values < 0.05). Red dots for upregulated and green for downregulated genes. b Venn diagram exhibited overlapped DEGs in shMETTL3-RNA-seq and m6A methylated transcripts in m6A RIP-seq. c Top terms identified by Gene Ontology enrichment analysis of overlapped genes including biological processes (BP), cellular components (CC), and molecular functions (MF). d Scatter plots of the top items analyzed in Gene Ontology enrichment

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