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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: METTL3-mediated m6A modification regulates cell cycle progression of dental pulp stem cells

Fig. 5

Alteration of METTL3 expression disrupted cell cycle progression of DPSCs. Flow cytometry detected the distribution of DPSC cell cycle phase after METTL3 knockdown by two independent METTL3-shRNA lentiviruses. a shCTR-1 and shMETTL3-1 treated DPSCs. b shCTR-2 and shMETTL3-2 treated DPSCs. c Cell cycle phase portions in METTL3-overexpressed DPSCs analyzed with flow cytometry. Data are represented as mean ± SD (n = 3), Student’s t test. *p < 0.05. **p < 0.01. ***p < 0.001

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