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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Characterization of stable hypoxia-preconditioned dental pulp stem cells compared with mobilized dental pulp stem cells for application for pulp regenerative therapy

Fig. 3

Anti-apoptotic and immunomodulatory activities of hpDPSCs and MDPSCs. a Anti-apoptotic activity showing Caspase-3 activity of hpDPSCs and MDPSCs in response to G-CSF. b Anti-apoptotic effect of hpDPSC and MDPSC CM in the staurosporine-treated canine PDLCs. c Immunomodulation activity of hpDPSCs and MDPSCs under homeostasis condition. d–h Immunomodulatory activity of hpDPSCs and MDPSCs when stimulated with IFN-γ. d IDO, e PTGE, f TGF-β, and g IL-6 mRNA expression. h Nitric oxide in the hpDPSC CM and the MDPSC CM. *p < 0.05, **p < 0.01, and ***p < 0.001. All data are expressed as the means ± standard deviation (n = 3)

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