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Fig. 10 | Stem Cell Research & Therapy

Fig. 10

From: Ultrasound enhances the therapeutic potential of mesenchymal stem cells wrapped in greater omentum for aristolochic acid nephropathy

Fig. 10

Schematic illustration of the involvement of the TGF-β/Smad signaling pathway in the therapeutic anti-fibrotic mechanisms of MSCs. MSCs downregulated the expression of Col-I, FN, and α-SMA by reducing TGF-β and p-Smad2 levels through the secretion of a wide variety of cytokines, chemokines, growth factors, and exosomes or microvesicles

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