Fig. 13

Anti-inflammatory effect of MSCs at 8 weeks after AAN induction in mice. Immunofluorescence staining for CD68 and CD206 in kidney tissues from the sham+saline, sham+MSC, AAN-saline, and AAN-MSC groups. The magnification for CD68 and CD206 staining was 400X (scale bar, 400 μm). Immunohistochemical staining confirmed the decrease in CD68+ cell numbers and the increase in CD206+ cell numbers in the AAN-MSC group compared with the AAN-saline group. Data are presented as the means ± SEM (n = 8). *P < 0.05 for the comparison between AAN-saline and AAN-MSC mice