Fig. 7

MSCs ameliorate renal injury induced by AA-I. a PAS staining of the kidney showing different grades of tubular injury at week 8 in sham+saline, sham+MSCs, AAN + saline, AAN + saline/c-lat, AAN + MSCs, and AAN + MSCs/c-lat mice. After the MSC treatment, the area of deposition in AAN-MSC mice was significantly smaller than that in AAN-saline mice. b Bar graphs showing the percentage of PAS score in each grade. A higher percentage of higher scores was observed in the AAN-saline group than in the AAN-MSC group. A significant difference was not observed between the omentum-wrapped kidney (the left kidney) and contralateral kidney (the right kidney). Score of 0: < 1%; score of 1: 1–5%; score of 2: 6–10%; score of 3: 11–20%; and score of 4: 21–50%. Data are presented as the means ± SEM (n = 8). Scale bar = 400 μm