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Fig. 9 | Stem Cell Research & Therapy

Fig. 9

From: Ultrasound enhances the therapeutic potential of mesenchymal stem cells wrapped in greater omentum for aristolochic acid nephropathy

Fig. 9

MSCs ameliorated kidney fibrosis in mice. a The mRNA expression levels of the fibrosis-related genes TGF-β, Col-I, and FN in the sham+saline, sham+MSC, AAN-saline, and AAN-MSC groups detected using qPCR. b Western blots showing the levels of TGF-β, Col-I, and α-SMA in the kidneys from the sham+saline, sham+MSC, AAN-saline, and AAN-MSC groups. The quantitative analysis of mRNA expression showed lower expression of TGF-β, Col-I, and FN in the AAN-MSC group than in the AAN-saline group. The quantitative analysis of protein expression showed lower expression of TGF-β, α-SMA, and Col-I in the AAN-MSC group than in the AAN-saline group. Data are presented as the mean ± SEM (n = 8). *P < 0.05 for the comparison between AAN-saline and AAN-MSC mice

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