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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Reprogrammed mesenchymal stem cells derived from iPSCs promote bone repair in steroid-associated osteonecrosis of the femoral head

Fig. 5

The osteogenesis-promoting effects of iPSC-MSCs on the SD rat model of MPS-induced ONFH. a Micro-CT imaging of the femoral head of each treatment group at 4 weeks and 8 weeks after the operation. b Micro-CT quantitative analysis of BMD, BV/TV, Tb.Sp, Tb.N, and Tb.Th (n = 5 per group). c Trabeculae and osteocytes analysis by HE staining for each treatment group at 4 weeks and 8 weeks after the operation. d Distinction of mature bone (red) and regenerated cartilage (blue) by Masson staining. Scale bar indicated 100 μm in all panels. All data are presented as mean ± SEM. Statistical differences were calculated using unpaired t test (*p < 0.05; **p < 0.01; ***p < 0.0001)

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Stem Cell Research & Therapy

ISSN: 1757-6512