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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Apoptosis repressor with caspase recruitment domain (ARC) promotes bone regeneration of bone marrow-derived mesenchymal stem cells by activating Fgf-2/PI3K/Akt signaling

Fig. 3

Ectopic new bone formation and cell apoptosis detection in nude mice. Cells were seeded into CPC scaffolds and then implanted subcutaneously for 8 weeks. a Both HE staining and OCN immunohistochemistry analysis confirmed the newly formed bone tissues in each group. b The percentage of new bone formation area in each group (**p < 0.01). c Immunofluorescence staining was carried out to detect cell apoptosis. Nuclei were stained with DAPI. Cell apoptosis was detected by a TUNEL kit and stained red. ARC protein was stained pink

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Stem Cell Research & Therapy

ISSN: 1757-6512