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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Transplantation of human amniotic epithelial cells promotes morphological and functional regeneration in a rat uterine scar model

Fig. 3

hAEC transplantation improved the recovery of endometrium and myometrium in scarred uteruses. a H&E staining of uterine scars at day 30 and 60 post-transplantation in the sham group, PBS group, and hAECs group (n = 8 uterine horns per group). Red arrows indicated repair sites. Scale bars = 500 μm. b Statistical analysis of the endometrial thickness in the uterine scars. c Statistical analysis of the number of endometrial glands per cross-section of the uterus. d Immunohistochemical (IHC) staining of α-smooth muscle actin (α-SMA) for smooth muscle abundance in uterine scars at day 30 and 60 post-transplantation in the sham group, PBS group, and hAECs group (n = 8 uterine horns per group). Red arrows indicated repair sites. Scale bars = 500 μm. e Statistical analysis of the percent of α-SMA-positive areas (α-SMA-positive area in the selected region/total α-SMA-positive area) measured by Image-Pro Plus software (*P < 0.05; **P < 0.01; ***P < 0.001; NS, P ≥ 0.05)

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