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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Transplantation of human amniotic epithelial cells promotes morphological and functional regeneration in a rat uterine scar model

Fig. 8

hAEC transplantation improved pregnancy outcomes in the uterine scar rat model. a Pregnancy outcome in uterine horns of female rats 90 days after injury in different groups. Similar size and shape of implanted fetuses were observed in the sham group; however, in the PBS group, there was no fetus implanted in the uterine scar. After hAEC transplantation, implanted fetuses were observed in the scarred area and were of similar size and shape to the fetuses implanted in the healthy area. Black arrows showed implanted fetuses and white arrows indicated the pre-marked margins of the uterine scar. b The total fetus number per uterine horn in the PBS group and hAECs group were smaller significantly than that in the sham group. c The number of fetuses implanted within the scarred area in the hAECs group was significantly larger than that in the PBS group. Data were presented as median, minimum, maximum, and individual data points (***P < 0.001; ****P < 0.0001; NS, P ≥ 0.05)

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