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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Low-dose IL-34 has no effect on osteoclastogenesis but promotes osteogenesis of hBMSCs partly via activation of the PI3K/AKT and ERK signaling pathways

Fig. 2

Low-dose IL-34 prompts activation of PI3K/AKT and ERK signaling during osteoblastogenesis in hBMSCs. a–g Western blotting analysis on days 3 and 7 was performed to determine the expression of NF-κB, MAPK, PI3K/AKT, and Wnt/β-catenin signaling pathways proteins on osteoblastogenesis. All of the experiments were independently accomplished no less than three times. Data are means ± SD. *P < 0.05 vs. the control group on day 3, #P < 0.05 vs. the control group on day 7, &P < 0.05 vs. the 3 days group at the same concentration

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