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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice

Fig. 2

Survival rates and blood of serum creatinine and urea nitrogen (BUN) levels of cisplatin-administered mice that were pretreated with or without G-CSF and/or AMD3100. a C57BL/6 mice received an injection of G-CSF (200 μg/kg/day), G-CSF (200 μg/kg/day)/AMD3100 (5 mg/kg), or saline (as control) into the intraperitoneal before treated with cisplatin. Mice were observed to determine the survival rate (n = 12, per group). b Serum creatinine and c serum BUN levels of the mice 4 days after cisplatin injection are shown. “Untreated” means mice without treatment with cytokine and cisplatin. Results are expressed as mean ± SD. *P < 0.05, **P < 0.01 and *** P < 0.001

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