Fig. 5

iMSCs-EVs administration downregulated the overexpression of COX-2 and prostaglandin E2. a Representative fluorescence images of COX-2 expression in prostatic tissues. COX-2⁺ cells were stained red. Nuclei were stained blue. Scale bar = 200 μm. b Statistical results of the numbers of COX-2⁺ cells. c, d Western blotting was utilized to quantify COX-2 protein levels in prostatic tissues. e The levels of prostaglandin E2 were determined by ELISA. Data are presented as the mean ± SD, *P < 0.05, n.s. indicates no significance