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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Adipose-derived mesenchymal stem cells attenuate dialysis-induced peritoneal fibrosis by modulating macrophage polarization via interleukin-6

Fig. 4

ADSC reversed macrophages M2/M1 ratio decreasing. a Represented IHC photographs were shown iNOS (M1 macrophage marker) staining and Arg-1 (M2 macrophage marker) staining. Cell nuclei were counterstained with hematoxylin. b The iNOS and Arg-1 stained cells were counted from IHC staining. Data were presented as mean ± SEM. Control group n = 3 and the others n = 6. ANOVA, p < 0.05, different characters represent different levels of significance. Scale bar = 50 μm. Abbreviations: CtrL control, MGO methylglyoxal, BM-MSC bone marrow-derived mesenchymal stem cell, ADSC adipose-derived mesenchymal stem cell, iNOS inducible nitric oxide synthase, Arg-1 arginase 1

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