Fig. 1

MSC SLP attenuated BLM-induced ALI in vivo. a Scheme representation of the mouse model established in this study. PBS, BLM (2.5 mg/kg), or BLM (2.5 mg/kg) plus MSC SLP (50 mg/kg) was intratracheally administered to mice. b Survival curves. Mortality of both CON and BLM + SLP group was zero. c Mouse weights on days 0, 4, and 7. d H&E staining. e–h Quantitative analysis of lung damage as assessed histopathologically. e Lung injury score. f Mean alveolar septal thickness (MAST). g Mean linear intercept (MLI). h Destructive index (DI). Ten fields were randomly selected for scoring. N = 6–8 in each group. The data shown are presented as the mean ± SD, and statistical differences were assessed by one-way ANOVA. *P < 0.05; **P < 0.01; ***P < 0.001