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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Lyophilized powder of mesenchymal stem cell supernatant attenuates acute lung injury through the IL-6–p-STAT3–p63–JAG2 pathway

Fig. 7

MSC SLP increased JAG2 expression by activating p63. a JAG2 mRNA-expression levels in a mouse model of ALI. b The protein-expression levels of JAG2 and β-actin in a mouse model of ALI. c Quantitative analysis of JAG2 expression. d The protein-expression levels of JAG2 and β-actin in mice treated with IL-6 ± SLP. e Quantitative analysis of JAG2 expression. f Schematic model of how MSC SLP attenuates BLM-induced ALI. N = 6–8 in each group. The data shown are presented as the mean ± SD, and statistical differences were assessed by one-way ANOVA. **P < 0.01; ***P < 0.001

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