Skip to main content
Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Use of constitutive and inducible oncogene-containing iPSCs as surrogates for transgenic mice to study breast oncogenesis

Fig. 8

Oncogene-containing iPSCs as surrogates for transgenic mice. Schematic depicts the use and efficacy of using these iPSC clones to duplicate both breast ontogenesis and breast oncogenesis occurring in the transgenics but only when injected orthotopically. These iPSC clones not only represent a transgenic surrogate model of breast cancer but one that allows for a more precise study of both differentiation and transformation

Back to article page