Fig. 8

The effect of ADSC-Exo or IL-17RA siRNA on Smad pathway in HSFs. a–c Immunoblot analysis of SIP1, p-Smad2, and p-Smad3 in HSFs stimulated with ADSC-Exo or PBS, graphs showed the relative band density to β-actin or total Smad2/3, respectively. The data was shown as mean ± SEM (*p < 0.05; **p < 0.01). d–f Immunoblot analysis of SIP1, p-Smad2, and p-Smad3 in HSFs treated with IL-17RA siRNA or scramble siRNA, graph showed the relative band density to β-actin or total Smad2/3, respectively. The data was shown as mean ± SEM (**p < 0.01). g Schematic diagram of the experimental results