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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Secretomes of human pluripotent stem cell-derived smooth muscle cell progenitors upregulate extracellular matrix metabolism in the lower urinary tract and vagina

Fig. 1

Gene expression of extracellular matrix (ECM) metabolism proteins in pSMC-CM-treated bSMCs and vaginal fibroblasts (ac). Gene expression levels of TIMP-2 (a), MMP-2 (b), and TIMP-1 (c) were analyzed by quantitative real-time RT-PCR in bSMCs from three women (B1, B2, B3) and vaginal fibroblasts from three women (F1, F2, F3). Data shown represent the mean ± SD from three independent experiments. Huf5-CM conditioned medium from Huf5 iPSC-derived pSMCs, BIR-CM conditioned medium from BIR iPSC-derived pSMCs, SMGS = SMGS only, no CM treatment (controls). *Significant difference between groups (p < 0.05)

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