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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Secretomes of human pluripotent stem cell-derived smooth muscle cell progenitors upregulate extracellular matrix metabolism in the lower urinary tract and vagina

Fig. 2

TIMP-1 and TIMP-2 protein expression in the supernatant of the bSMCs (a) and vaginal fibroblasts (b) treated with pSMC-CM. Each bar plot represents 6 separate experiments run on 6 gels to illustrate the statistical trends for each experiment. Each experiment consists of the SMGS-media-only, SMGS, CM at P0, and CM at P3 groups (black, orange, blue, and pink bars). The expression levels for each bar can be compared within each experiment, but not between experiments. Data shown represent the mean ± SD from three independent experiments. Huf5-CM conditioned medium from Huf5 iPSC-derived pSMCs, BIR-CM conditioned medium from BIR iPSC-derived pSMCs, SMGS supernatant from bSMC or vaginal fibroblasts treated with SMGS only, SMGS media only = concentrated SMGS media only. *Significant difference between groups (p < 0.05)

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Stem Cell Research & Therapy

ISSN: 1757-6512