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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Secretomes of human pluripotent stem cell-derived smooth muscle cell progenitors upregulate extracellular matrix metabolism in the lower urinary tract and vagina

Fig. 6

Gene expression of rat-collagen I, rat-collagen III, rat-elastin, TIMP-2, and MMP-2 (a) and protein expression of rat-collagen III and rat-elastin in conditioned medium treated rat urethras for each group (b). Data shown represent the mean ± SD. Pure control = rats with no surgery and no treatment; Sham SMGS = SUI rats treated with concentrated SMGS only; H9 CM = SUI rats treated with conditioned medium from H9 ESC-derived pSMC; Huf5 CM = SUI rats treated with conditioned medium from Huf5 iPSC-derived pSMCs; BIR CM = SUI rats treated with conditioned medium from Huf5 iPSC-derived pSMCs. *Significant difference between groups (p < 0.05)

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Stem Cell Research & Therapy

ISSN: 1757-6512