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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Secretomes of human pluripotent stem cell-derived smooth muscle cell progenitors upregulate extracellular matrix metabolism in the lower urinary tract and vagina

Fig. 8

Effect of pSMC-CM on the muscle layer of the rat apical vagina wall. Representative images of cross-section of proximal vagina (apical vagina). Pink stains are tissue stains for collagen/elastin to show tissue structure. Green/blue stains are immunofluorescence stains of the same section with smoothelin staining for smooth muscle cells (green) and DAPI stain for cell nucleus (blue). Pure control = rats with no surgery and no treatment; Sham SMGS = SUI rats treated with concentrated SMGS only; H9 CM = SUI rats treated with conditioned medium from H9 ESC-derived pSMC; Huf5 CM = SUI rats treated with conditioned medium from Huf5 iPSC-derived pSMCs; BIR CM = SUI rats treated with conditioned medium from Huf5 iPSC-derived pSMCs

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Stem Cell Research & Therapy

ISSN: 1757-6512