Skip to main content

Table 3 Azoospermia treated with mesenchymal stromal/stem cells in in vivo model studies

From: Mesenchymal stromal/stem cells and their exosomes for restoration of spermatogenesis in non-obstructive azoospermia: a systemic review

Source

Transplantation

Donor species

Therapeutics

Recipient species

Modeling

References

Adipose tissue

Allotransplant

Hamster

Cell

Hamster

Busulfan

[121]

Adipose tissue

Allotransplant

Mouse

Cell

Exosome

Mouse

Busulfan

[122]

Adipose tissue

Allotransplant

Rat

Cell

Rat

Busulfan

[70, 123, 124]

Adipose tissue

Allotransplant

Rat

Cell

Rat

Cisplatin

[125]

Adipose tissue

Xenotransplant

Human

Cell

Rat

Torsion

[126]

Amnion

Allotransplant

Mouse

Cell

Mouse

Busulfan

[127]

Bone marrow

Allotransplant

Guinea pig

Cell

Guinea pig

Busulfan

[128]

Bone marrow

Allotransplant

Hamster

Cell

Hamster

Busulfan

[129]

Bone marrow

Allotransplant

Mouse

Cell

Mouse

Busulfan

[130, 131]

Bone marrow

Allotransplant

Mouse

Cell

Exosome

Mouse

Busulfan

[122]

Bone marrow

Allotransplant

Mouse

Cell

Mouse

Cisplatin

[132]

Bone marrow

Allotransplant

Rat

Cell

Rat

Busulfan

[87, 89, 133,134,135,136,137,138]

Bone marrow

Allotransplant

Rat

Cell

Rat

Doxorubicin

[139]

Bone marrow

Allotransplant

Rat

Cell

Rat

Lead nitrate

[140]

Bone marrow

Allotransplant

Rat

Cell

Rat

Torsion

[141]

Bone marrow

Xenotransplant

Goat

Cell

Mouse

Busulfan

[142]

Umbilical cord

Xenotransplant

Human

Cell

Mouse

Busulfan

[143,144,145]

Urine

Allotransplant

Mouse

Cell

Exosome

Mouse

Busulfan

[146]