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Table 4 Clinical trials on mesenchymal stromal/stem cells-based therapy for female and male reproductive diseases (U. S. National Library of Medicine)

From: Mesenchymal stromal/stem cells and their exosomes for restoration of spermatogenesis in non-obstructive azoospermia: a systemic review

Sex Disease/syndrome Phase Date Country Source Transplantation Stage CT code
Female Atrophic endometrium 2 2019 Russia Bone marrow Autotransplant Completed NCT03166189
Female Fistula vagina 1 2020 United States ND Autotransplant Completed NCT03220243
Female Intrauterine adhesions
Endometrial dysplasia
4 2014 China Bone marrow Autotransplant ND NCT02204358
Female Intrauterine adhesions ND 2014 China Umbilical cord Allotransplant Completed NCT02313415
Female Intraventricular hemorrhage 2 2017 Korea Umbilical cord Allotransplant Recruiting NCT02890953
Female Ovarian cancer 1 2019 United States ND Autotransplant Completed NCT02530047
Female Ovarian disease 1&2 2015 Jordan Bone marrow Autotransplant Active NCT03069209
Female Premature ovarian failure 1&2 2018 China Umbilical cord Allotransplant Completed NCT02644447
Female Premature ovarian failure 1&2 2014 Egypt Bone marrow Autotransplant ND NCT02696889
Female Premature ovarian failure ND 2016 United States Bone marrow Autotransplant Active NCT02696889
Female Thin endometrium 1 2018 China Umbilical cord Allotransplant Recruiting NCT03592849
Female Thin endometrium 1 2020 Indonesia Endometrium Autotransplant Recruiting NCT04676269
Female Uterine scar 2 2020 China Umbilical cord Allotransplant Recruiting NCT02968459
Female Uterine scar 1 2020 China Umbilical cord Allotransplant Recruiting NCT03181087
Female Uterus injury 2 2020 China Umbilical cord Allotransplant Recruiting NCT03386708
Male Azoospermia ND 2015 Egypt Bone marrow Autotransplant Completed NCT02414295
Male Azoospermia 1&2 2014 Egypt Bone marrow Autotransplant ND NCT02025270
Male Azoospermia ND 2013 Egypt Bone marrow Autotransplant Recruiting NCT02008799
Male Azoospermia 1&2 2014 Egypt Bone marrow Autotransplant Recruiting NCT02041910
Male Azoospermia 1&2 2015 Jordan Bone marrow Autotransplant Recruiting NCT02641769
Male Azoospermia
Oligospermia
2 2018 Russia Adipose tissue Autotransplant Recruiting NCT03762967
Male Erectile dysfunction 1 2018 Jordan Wharton’s Jelly Allotransplant Completed NCT02945449
Male Erectile dysfunction 1&2 2019 Jordan Wharton’s Jelly Allotransplant Completed NCT03751735
Male Erectile dysfunction 1 2018 Korea Bone marrow Autotransplant Completed NCT02344849
Male Erectile dysfunction 2 2020 Korea Bone marrow Autotransplant Recruiting NCT04594850
  1. ND no data