Skip to main content
Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Human bone marrow-derived stromal cell behavior when injected directly into the bone marrow of NOD-scid-gamma mice pre-conditioned with sub-lethal irradiation

Fig. 2

hBMSC-Luc/GFP engraftment in a Non-irradiated and b 2 Gy Irradiated mice detected by immunohistochemistical staining of mouse injected and contralateral femurs at week 4, post-transplant. Scale bar equals 20 μm. c The percentage of hBMSC-Luc/GFP detected in the bone marrow cavities of non-irradiated (blue) or irradiated mice (red). d The distribution of hBMSC-Luc/GFP in relation to the endosteal region. e The proportion of hBMSC-Luc/GFP that are within 3 cell diameters of another hBMSC-Luc/GFP. Each data point represents a single mouse, and the horizontal bar represents the group average. For some animals, we were unable to capture sufficiently high-quality histology images, and in these instances, histology data for these animals is not reported. High-quality histology was captured for n = 8 non-irradiated mice, and n = 10 irradiated mice. Significance was tested using 2-way ANOVA with the Holm-Sidak’s multiple comparison test between groups

Back to article page