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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: MSC-derived small extracellular vesicles overexpressing miR-20a promoted the osteointegration of porous titanium alloy by enhancing osteogenesis via targeting BAMBI

Fig. 2

sEV-20a promotes the migration and osteogenic differentiation of hBM-MSCs in vitro. a Proliferation of hBM-MSCs cultured with sEV-20a by CCK-8 assay. b-c Cell migration of hBM-MSCs cultured with sEV-20a by transwell assay. Scale bar = 100 μm.ALP staining and ARS were applied for the assessment of osteogenic differentiation of hBM-MSCs by different treatments. Scale bar = 200 μm. d-f Relative gene expressions for ALP, RUNX2, OCN of hBM-MSCs by different treatments. GAPDH was used for normalization (*p < 0.05)

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