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Fig. 9 | Stem Cell Research & Therapy

Fig. 9

From: MSC-derived small extracellular vesicles overexpressing miR-20a promoted the osteointegration of porous titanium alloy by enhancing osteogenesis via targeting BAMBI

Fig. 9

Schematic diagram depicts the detailed mechanisms of miR-20a on pro-osteogenesis and pro-osteointegration effects. In vitro, sEV-20a was successfully established and proved to promote the migration and osteogenesis of hBM-MSCs. In vivo, sEV-20a promoted osteointegration in an osteoporotic rat model. In addition, we proved that miR-20a could enhance osteogenesis by targeting BAMBI

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Stem Cell Research & Therapy

ISSN: 1757-6512