Table 3 Outcomes (OS, TRM/NRM, RR) of included studies

Author, year

P value

Follow-up, months

Survival

Follow-up, months

Survival

Ball, 2007 [16]

Range 3–28

OS 72%

Range 32–110

OS 63%

Not reported

RR 18%

RR 26%

Not reported

Daganzo, 2009 [30]

Median 7.4, range 1–22

OS 89%

Median 24, range 1–107

OS 53%

= 0.19

RR 11% at 22 months

RR 13% at 60 months

Not reported

DFS 71%

DFS 45%

Not reported

TRM 11% (95% CI 2–71)

TRM 37% (95% CI 25–54)

Not reported

Wu, 2013b [28]

Median 16.5, range 11–27

OS 75%

Median 18.5, range 12–31

OS 67%

> 0.05

RR 25%

RR 16.67%

Not reported

TRM 25%

TRM 33%

> 0.05

Wu, 2013a [34]

Median 27, range 24–31

OS 80%

Not reported

OS 56%

= 0.58

TRM 0%

TRM 22.2%

= 0.51

Author, year

P value

Measure time point, years

Survival

Measure time point, years

Survival

Baron, 2010 [32]

1

OS 60%

1

OS 38%

= 0.1

DFS 5%

DFS 0%

> 0.05

TRM 10%

TRM 37%

= 0.02*

RR 30%

RR 25%

= 0.9

Zhang, 2015 [37]

1

OS 72.7%

1

OS 85.2%

= 0.472

RR 9.1%

RR 22.2%

= 0.396

CRR 9.1%

CRR 33.3%

= 0.093*

Xiang, 2017 [13]

1

OS 87%

1

OS 75%

= 0.202

CRR 16%

CRR 25%

= 0.351

Lee, 2013 [14]

2

OS 85.7%

2

OS 55.6%

= 0.15

Liu, 2011 [22]

2

OS 69.7%

2

OS 64.3%

= 0.737

RR 12.8%

RR 9.3%

= 0.721

MacMillan, 2009 [31]

3

OS 75% (95% CI 45–100)

3

OS 46% (95% CI 26–66)

= 0.38

Ning, 2008 [24]

3

OS 40%

3

OS 66.7%

Not reported

DFS 30%

DFS 66.7%

= 0.035*

RR 60.0%

RR 20%

= 0.020*

Bernardo, 2011 [15]

3

OS 63% (95% CI 43–97)

3

OS 64% (95% CI 48–79)

NS

DFS 67% (95% CI 41–94)

DFS 56% (95% CI 40–72)

NS

TRM 8% (95% CI 1–51)

TRM 21% (95% CI 11–38)

NS

RR 25% (95% CI 9–67)

RR 23% (95% CI 13–42)

NS

Kang, 2017 [38]

3

OS 70.6%

3

OS 23.1

= 0.004*

DFS 52.9%

DFS 0%

= 0*

TRM 11.8%

TRM 46.2%

= 0.017*

RR 32.4%

RR 53.8%

= 0.199

Ghavamzadeh, 2017 [39]

3

OS 70%

3

OS 61%

= 0.78

DFS 54%

DFS 61%

= 0.35

Mareika, 2016 [29]

> 3

OS (90 ± 9.5)%

> 3

OS (83 ± 10.7)%

Not reported

RR 10%

RR 0%

Not reported