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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: CD157 in bone marrow mesenchymal stem cells mediates mitochondrial production and transfer to improve neuronal apoptosis and functional recovery after spinal cord injury

Fig. 5

CD157 overexpression in BMSCs attenuates inflammation and apoptosis of the injured neurons in vivo (1). a Schematic diagram of the spinal cord. b BBB scores of injured rats (n = 6). *p < 0.05, &p < 0.05 vs SCI+Mock group; ####p < 0.001 vs SCI+shRNA group. Representative c Nissl staining images of the spinal cord. The red rectangle showed the injured site. Scale bar, 250 μm. d, f Representative immunofluorescence images of Grp 78 and NF-κB of neurons at the injured site. The white arrows indicate the positive cells. Scale bars, 100 μm. e Statistics of Grp 78 positive rate. n.s., non-significant, ****p < 0.0001 vs SCI group. #p < 0.05, ####p < 0.0001 vs Mock group. g Statistics of NF-κB intranuclear content. *p < 0.05, ****p < 0.0001 vs SCI group. #p < 0.05, ##p < 0.01 vs Mock group

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