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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: CD157 in bone marrow mesenchymal stem cells mediates mitochondrial production and transfer to improve neuronal apoptosis and functional recovery after spinal cord injury

Fig. 7

CD157/ADPR-cyclase activity and Ca2+ signal in BMSCs. a Confirmation of CD157/ADPR-cyclase activity (n = 5, fold of 0 nM). *p < 0.05. b Statistics for the mitochondria content in BMSCs pre-stained using Mito Tracker Red CMXRos (n = 5, fold of 0 nM). **p < 0.01, ***p < 0.001. c Statistics for the ATP content in BMSCs subjected to cADPR at different concentrations (n = 3, fold of 0 nM). *p < 0.05, ***p < 0.001, ****p < 0.0001. d Statistics for the Ca2+ signal in BMSCs subjected to cADPR at different concentrations (n = 3, fold of 0 nM). *p < 0.05, **p < 0.01. e CD157/ADPR-cyclase activity detect of different BMSCs (n = 3, fold of Mock group). *p < 0.05, **p < 0.01. f Statistics for the mitochondria content in different BMSCs (n = 3, fold of Mock group). *p < 0.05. g Statistics for the Ca2+ signal of transfected BMSCs when co-cultured with OGD VSC4.1 motor neurons (n = 4, fold of OGD group). n.s., non-significant, **p < 0.01, ****p < 0.0001 vs OGD group. #p < 0.05, ###p < 0.001 vs Mock group

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