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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Andrographolide promotes proliferative and osteogenic potentials of human placenta-derived mesenchymal stem cells through the activation of Wnt/β-catenin signaling

Fig. 5

Effect of AP on osteoblast-marker gene expressions during osteoblast differentiation. The mRNA expressions of osteoblast marker genes in PL-hMSC-derived osteoblastic cells after culture in osteogenic media with or without AP at the indicated concentrations and times: Expressions of mRNA were determined relative to GAPDH by quantitative RT-PCR. a RUNX2 (day 7). b OSX (day 7). c ALP (day 14). d Col1a1 (day14). e Osteocalcin (day 21). f OPG (day 21). g RANKL (day 21). h The ratio of RANKL/OPG (day 21). Each value is the mean ± SEM; (n = 3). *P < 0.05, **P < 0.01, compared to the control group

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Stem Cell Research & Therapy

ISSN: 1757-6512