Skip to main content
Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p

Fig. 1

Experimental outline of IL-1β-induced osteoarthritic chondrocytes (OA-CH) treated with curcumin-primed hBMSC-derived EVs (Cur-EVs). The aim of this study was to evaluate the effect of Cur-EVs on OA-CH. OA-CH were stimulated with IL-1β to establish a standard in vitro OA model. Cur-EVs were used as a cell-free therapeutic approach to treat IL-1β-stimulated OA-CH. We hypothesize that Cur-EVs could reverse the catabolic effects induced by IL-1β in OA-CH by inhibiting inflammatory related signaling pathways

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512