Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: A randomized, controlled clinical trial of autologous stromal vascular fraction cells transplantation to promote mechanical stretch-induced skin regeneration

Fig. 5

Histology and immunohistochemical staining of the expanded skin. HE staining showed that the epidermal layer in the SVF group was thicker than that in the control group (a) with the presence of an increasing rete subpapillary in the papillary layer. Masson’s trichrome staining showed that the ECM volume in the SVF group was significantly increased as the collagen fibers showed an organized distribution, whereas the collagen fibers in the control group (b) were loosely organized. PCNA + proliferating cells and CD31+ stained vessels were significantly increased in the SVF group compared to the control group (c, d). The results of the statistical analysis showed more proliferating cells (e) and blood vessels (f) in the SVF-treated skin as the volume of ECM increased (g). Scale bar in ad, 100 μm. *p<0.05, **p<0.01

Back to article page