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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Small extracellular vesicles from human adipose-derived mesenchymal stromal cells: a potential promoter of fat graft survival

Fig. 6

hADMSC-sEVs promoted neovascularization in the nude mice fat grafting model (rows means different staining and lines represents different groups and months). CD34 was selectively expressed in the small vessel endothelium membrane. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. The VEGFR2 was mainly localized in membrane. Signs of proliferation (nuclei stained by Ki-67) in the vessel endothelium (blue line at the bottom left of each figure represents scale bar; scale bar = 50 μm)

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