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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Heat shock preconditioning mesenchymal stem cells attenuate acute lung injury via reducing NLRP3 inflammasome activation in macrophages

Fig. 2

HS-pretreated UC-MSCs attenuate LPS-induced ALI. a Hematoxylin and eosin staining of lung tissues in each group to assess the amount of lung damage after ALI. Scale bar 200 μm. b The lung injury score of each group was calculated by selecting five fields in each section. The results are presented as the mean ± SEM (n = 5 mice/group). c The wet/dry ratio of lung tissue of each group was obtained to evaluate lung edema. The results are presented as the mean ± SEM (n = 5 mice/group). d The total cell count and neutrophil count in the BALF from each group were examined at 24 h after LPS treatment to assess the inflammatory response. The results are presented as the mean ± SEM (n = 5 mice/group). e Representative images of TUNEL staining of lung sections from each group were collected. Scale bar 200 μm. The data are presented as the mean ± SEM (n = 5 mice/group). *p < 0.05, **p < 0.01, ***p < 0.001 (all p values were obtained by one-way ANOVA)

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Stem Cell Research & Therapy

ISSN: 1757-6512