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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Role of CD44 in increasing the potency of mesenchymal stem cell extracellular vesicles by hyaluronic acid in severe pneumonia

Fig. 1

MSC-derived Extracellular Vesicles and Influence of Molecular Weight of Hyaluronic Acid on EV Binding. a Mean size and size distribution of MSC EV by NanoSight analyses. b Binding ability of different molecular weights of HA with MSC EV. PKH26-labeled MSC EV preferentially bound to HMW HA (1.0 MDa) compared with PBS, LMW HA (40 KDa), or HMW HA (1.5 MDa). Data are mean ± SD, ****P < 0.0001 by ANOVA (Bonferroni), N = 19–28. Dose of MSC EV (50 μl) used = 1.1 × 1010 particles

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