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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Human bone marrow-derived, pooled, allogeneic mesenchymal stromal cells manufactured from multiple donors at different times show comparable biological functions in vitro, and in vivo to repair limb ischemia

Fig. 6

Stempeucel®-1 and Stempeucel®-1A treatment improved blood perfusion and capillary density in ischemic limbs. a, b Laser Doppler blood flow flux was measured in sham, LI + vehicle, and LI + two Stempeucel®-treated groups at 28 days after LI. ##P < 0.01, sham control vs LI vehicle; **P < 0.01, LI vehicle vs LI + Stempeucel®-1; *P < 0.05, LI vehicle vs LI + Stempeucel®-1A. c Capillary density at day 28 increased significantly in Stempeucel®-1- (**P < 0.001) and Stempeucel®-1A (**P < 0.01)-treated animals compared to vehicle-treated animals. Values are expressed as mean ± SEM. Scale bar = 50 μm, × 40 magnification

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