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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Human bone marrow-derived, pooled, allogeneic mesenchymal stromal cells manufactured from multiple donors at different times show comparable biological functions in vitro, and in vivo to repair limb ischemia

Fig. 7

Biodistribution kinetics of Stempeucel®-1 in sham and ischemia-induced BALB/c nude mice. a Heat map of DiI-labeled areas in the limb muscle of sham control and ischemic animals (one representative animal shown) at various time points after Stempeucel®-1 injection. RGB scale—1 × 107–10 × 107 photons/s/mm2. b Graphical representation of the average net intensity of DiI-labeled cells in the limb muscles of sham and ischemic animal groups on day 1, day 3, day 6, day 11, day 14, day 21, and day 28 (end of the experiment). Significantly higher intensity of DiI signal was observed in the ischemia-induced animal group on day 6 and 11 (*P = 0.01) compared to that of the sham group

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Stem Cell Research & Therapy

ISSN: 1757-6512