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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Upregulated anti-angiogenic miR-424-5p in type 1 diabetes (model of subclinical cardiovascular disease) correlates with endothelial progenitor cells, CXCR1/2 and other parameters of vascular health

Fig. 4

Ingenuity pathway analysis (IPA) prediction network of miR-424-5p using our data and its mRNA targets and cytokines supporting its involvement in cardiovascular disease. Three pathways were considered as relevant in this study: angiogenesis, haematopoiesis of monunuclear cells and insulin receptor signalling. CD, cluster of differentiation; COX2, cyclooxygenase-2; VEGF, vascular endothelial growth factor; CCND1, gene encoding cyclin D1; IL, interleukin, CXCR, chemokine receptors

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Stem Cell Research & Therapy

ISSN: 1757-6512