Characteristics | Healthy control group | T1DM | p value |
---|---|---|---|
N | 20 | 29 | Â |
Age (years) | 46.5 ± 11.7 | 47.2 ± 12.7 | 0.8 |
Body mass index (kg/m) | 26.0 ± 4.5 | 28.4 ± 6.7 | 0.3 |
Sex (M/F) | 9/11 | 14/15 | – |
Duration of diabetes (years) | – | 22.4 ± 13.9 | – |
HbA1C (mmol/mol) | 35.1 ± 2.8 | 57.3 ± 7.6 | < 0.001*** |
HbA1C (%) | 5.4 ± 0.3 | 7.4 ± 0.7 | |
Fasting blood glucose (mmol/L) | 4.6 ± 1.0 | 9.7 ± 3.7 | < 0.001*** |
Haemoglobin (g/dL) | 14. 3 ± 1.2 | 14.5 ± 1.2 | 1.0 |
Triglycerides (mmol/L) | 1.4 ± 0.7 | 0.9 ± 0.4 | 0.145 |
Alanine aminotransferases (IU/L) | 21.3 ± 6.1 | 22.8 ± 1.7 | 0.9 |
eGFR (ml/min/1.73m2) | 78.09 ± 10.05 | 83.5 ± 9.8 | 0.259 |
Systolic blood pressure (mmHg) | 117.5 ± 14.0 | 127.5 ± 9.4 | 0.005** |
Diastolic blood pressure (mmHg) | 74.8 ± 8.3 | 76.8 ± 8.8 | 0.3 |
CD45dimCD34+CD133+/100 lymphocytes (cEPCs) | 0.09 ± 0.03 | 0.02 ± 0.01 | < 0.001*** |
Proangiogenic cells (PACs) | 44.9 ± 22.3 | 14.4 ± 7.6 | < 0.001*** |
Fibronectin adhesion assay per hpf | 68.6 ± 34.5 | 33.9 ± 14.7 | 0.017** |