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Table 1 Body and lung weights and lung-to-body-weight ratios in 14-day-old rats exposed to RA or hyperoxia and treated with NS or surfactant on postnatal day 4 and NS or MSCs on postnatal day 5

From: Consecutive daily administration of intratracheal surfactant and human umbilical cord-derived mesenchymal stem cells attenuates hyperoxia-induced lung injury in neonatal rats

Treatment

n

Body weight

Lung weight

Lung to body weight ratio

  

(g)

(g)

(%)

RA + NS + NS

13

23.62 ± 2.57

0.41 ± 0.03

1.74 ± 0.21

RA + surfactant + NS

11

25.75 ± 4.94

0.45 ± 0.06

1.79 ± 0.20

O2 + NS + NS

5

23.22 ± 7.01

0.39 ± 0.17

1.64 ± 0.50

O2 + surfactant + NS

8

22.83 ± 4.62

0.42 ± 0.09

1.86 ± 0.26

O2 + surfactant + hUC-MSCs (3 × 104)

8

24.39 ± 7.07

0.46 ± 0.12

1.94 ± 0.47

O2 + surfactant + hUC-MSCs (3 × 105)

5

23.41 ± 1.67

0.40 ± 0.04

1.70 ± 0.13

  1. Values are presented as means ± standard deviations
  2. hUC-MSCs human umbilical cord-derived mesenchymal stem cells, NS normal saline, O2 oxygen-enriched atmosphere, RA room air