Fig. 2
Histologic analysis of GO animals treated with hPMSCsPRL-1 or steroid injection. ICAM-1 staining of orbital tissue, by orientating the paraffin block for sectioning with optic nerve as an anatomical landmark. ICAM-1 expressions were measured in a optic nerve, b lacrimal gland, and c extraocular muscle tissue of retrobulbar. The d thickness and e expansion of retrobulbar adipose tissue around the optic nerve were measured. Data was presented as the fold changes (means ± SEM) of thickness and adipose volume around optic nerve compared with the sham of each group. Significantly different values between groups are indicated with mark (*p < 0.05, **p < 0.01, ***p < 0.001 vs sham; #p < 0.05 vs normal). a–d Normal n = 6, GO n = 4; e n = 6/each group