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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: PRL-1 overexpressed placenta-derived mesenchymal stem cells suppress adipogenesis in Graves’ ophthalmopathy through SREBP2/HMGCR pathway

Fig. 4

hPMSCs PRL-1 co-culture inhibit adipogenesis in GO-derived OFs. a Representative images and b quantification of Nile red staining in differentiated OFs from normal and GO patients with naïve or hPMSCsPRL-1 co-culture for 24 h. c The mRNA expression of adipogenesis markers (e.g. ADIPSIN, ADIPONECTIN, LPL, LEPTIN, PPARγ, FABP4, C/EBPα, and C/EBPβ) by qRT-PCR. Significantly different values between the groups are indicated with marks (#p < 0.05 vs normal non-coculture (-); *p < 0.05 vs normal or GO-OF non-co-culture; **p < 0.05 vs hPMSCs)

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