Fig. 5
hPMSCsPRL-1co-culture regulate TSHR-SREBP2-HMGCR signaling pathway. The a mRNA, b protein expression, and c their quantifications of TSHR, active-SREBP2, and HMGCR in differentiated OFs from normal and GO patients with naïve or hPMSCsPRL-1 co-culture for 24 h. Significantly different values between the groups are indicated with marks (#p < 0.05 vs normal non-coculture (-); *p < 0.05 vs normal or GO-OF non-co-culture; **p < 0.05 vs hPMSCs)