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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Cardiac organoid — a promising perspective of preclinical model

Fig. 1

Essential signaling pathways and key factors for the construction of various organoids with pluripotent stem cells. FGF, fibroblast growth factor; BMP, bone morphogenetic protein; SAG, Hedgehog agonist smoothened agonist; SB431542, a TGFβ inhibitor; IWR1, a WNT inhibitor; CHIR99021, a GSK3β inhibitor; XAV939, a WNT inhibitor; EGF, epidermal growth factor; HGF, hepatocyte growth factor; VEGF, vascular endothelial growth factor

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