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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Clinical outcomes of modified simple limbal epithelial transplantation for limbal stem cell deficiency in Chinese population: a retrospective case series

Fig. 3

Representative images of case 3, in which epithelial regeneration was observed by IVCM and IC. a Slit-lamp biomicroscopy showing that the central cornea is transparent, with mild vascularization and conjunctivalization in the upper and nasal quadrants, and few implants are still visible. bd Superficial polygonal cells, intermediate wing cells, and smaller basal cells in the central part of the cornea. e Palisade-like structures were not detected in the limbal tissue. f Immature epithelial cells with small indistinct cell borders, bright nuclei, and a high nucleus-to-cytoplasm ratio that gradually proliferated and migrated into mature cells. g Mature epithelial cells with hyper-reflective and defined borders were formed around the graft. h Goblet cells (arrows) with strong PAS staining were distributed in the upper quadrant of polygonal corneal epithelial cells in IC. The frame size is 400 × 400 μm. LT, limbal tissue; IMC, immature cells; MC, mature cells

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